MRI conditional pacing system with MRI tested leads.1 Always one step ahead.

A pacing system known for small size, longevity, and high performance.



Making MRI scans easy and safe for pacemaker patients.1



Designed to promote intrinsic conduction in patients who need dual-chamber pacing.



Sleep Apnea Monitoring measures respiration pauses and reduction in respiration.


Dual Sensor

Designed to physiologically modulate heart rhythm by combining Accelerometer and Minute Ventilation sensors.

Kora 100 provides the first MRI mode that automatically detects an MRI magnetic field – another innovative solution in a pacing system known for small size, longevity, and high performance.

12 years longevity in only 8 cc.

The world’s smallest dual-chamber pacemaker with no compromise on longevity.2–4



Built on proven technology

Kora 100 is built on the heritage of Sorin pacemaker technology: the Reply platform. The Reply pacemaker platform has been proven in practice.5

Reply pacemakers:

  • 99.96% cumulative survival 6 years after implantation

Beflex leads:

  •  99.94% cumulative survival 5 years after implantation

Kora 100 is built on the Reply platform.

Powered by intelligent algorithms.


  • Less time, more flexibility1
  • Making MRI scans easy and safe for pacemaker patients1
  • Automatic switch to initial configuration
  • No post-MRI visit needed


  • Advanced AV management for increased protection6,8–14
  • Reduces RV pacing in SND and AVB patients6
  • Manages ALL types of AV blocks at rest and at exercise2,6
  • Adds 2 YEARS of device longevity13,14
  • Unique AV block diagnosis

Sleep Apnea Monitoring

  • Early detection, long-term risk reduction2,7,15–19
  • Reliable screening to detect severe Sleep Apnea with high specificity (85%) and high sensitivity (89%)7
  • Correlated with gold standard Apnea–Hypopnea Index*7
  • Designed to monitor the evolution of sleep apnea2

*Apnea Hypopnea Index (AHI) = number of events/number of hours of sleep


Dual Sensor

  • Adjust to metabolic needs. Exercise safely
  • Designed to physiologically modulate the heart rhythm by combining Accelerometer and Minute Ventilation sensors

This product is not available for sale or distribution in the USA. For further information on product availability, please contact your local representative.

Related products:

Orchestra Plus programmer; Leads; Vega; Xfine


  1. Sorin MRI Solutions implant manual (U201) available at
  2. Sorin Kora 100 implant manual (U199 KORA 100 DR /U200 KORA100 SR) available at
  3. REPLY DR Competitive Summary, Sorin Group, ULS4222C, October 2013.
  4. KORA 100 DR with typical conditions using SafeR: 50% A pacing, 5% V pacing, SAM ON, 60 min-1, 2.5V, 0.35ms, 750 ohms, EGM & Diagnostics ON, Rate response ON, Sensors ON. KORA 100 SR, 11.4 years of longevity in 7.5cc only with conditions: 100% V pacing, SAM ON, 60 min-1, 2.5V, 0.35ms, 750 ohms, EGM & Diagnostics on, Rate response on, Sensors on.
  5. Sorin Group; Product Performance Report. November 2014.
  6. Stockburger M, et al. Long-term clinical effects of ventricular pacing reduction with a changeover mode to minimize ventricular pacing in general population (ANSWER study). Eur Heart J. 2015;36:151–57.
  7. Defaye P, et al. A pacemaker transthoracic impedance sensor with an advanced algorithm to identify severe sleep apnea: The DREAM European study. Heart Rhythm. 2014;11:842–48.
  8. Andersen HR, et al. Long-term follow-up of patients from a randomized trial of atrial versus ventricular pacing for sick-sinus syndrome. Lancet. 1997;350:1210–16.
  9. Skanes AC, et al. Progression to chronic atrial fibrillation after pacing: The Canadian Trial Of Physiologic Pacing (CTOPP). J Am Coll Cardiol. 2001;38:167–72.
  10. Nielsen J, et al. A randomized comparison of atrial and dual chamber pacing in 177 consecutive patients with sick sinus syndrome. J Am Coll Cardiol. 2003;42:614–23.
  11. Sweeney M, et al. Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker therapy for sinus node dysfunction. Circulation. 2003; 107:2932–37.
  12. Wilkoff BL, et al. Dual-chamber pacing or ventricular backup pacing in patients with an implantable defibrillator: the Dual Chamber and VVI Implantable Defibrillator (DAVID trial). JAMA. 2002;288:3115–23.
  13. Stockburger M, et al. Safety and efficiency of ventricular pacing prevention with an AAI-DDD changeover mode in patients with sinus node disease or atrioventricular block: impact on battery longevity-a substudy of the ANSWER trial. Europace. 2016;18:739–46.
  14. Benkemoun H, Sacrez J, Lagrange P et al. Optimizing pacemaker longevity with pacing mode and settings programming: results from a pacemaker multicenter registry. Pacing Clin Electrophysiol 2012;35:403–08.
  15. Gottlieb DJ, Yenokyan G, Newman AB et al. Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the sleep heart health study. Circulation. 2010;122:352–60.
  16. Mehra R, Benjamin EJ, Shahar E et al. Association of nocturnal arrhythmias with sleep-disordered breathing: The Sleep Heart Health Study. Am J Respir Crit Care Med. 2006; 173(8): 910-6.
  17. Monahan K, Brewster J, Wang L, et al. Relation of the severity of obstructive sleep apnea in response to anti-arrhythmic drugs in patients with atrial fibrillation or atrial flutter. Am J Cardiol. 2012;110:369–72.
  18. Kanagala R, Murali NS, Friedman PA et al. Obstructive sleep apnea and the recurrence of atrial fibrillation. Circulation. 2003;107:2589–94.
  19. Ng CY, Liu T, Shehata M, Stevens S, Chugh SS and Wang X. Meta-analysis of obstructive sleep apnea as predictor of atrial fibrillation recurrence after catheter ablation. Am J Cardiol. 2011;108:47–51.
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